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Issue 34, 2014
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Red Si–rhodamine drug conjugates enable imaging in GFP cells

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Abstract

Here we evaluated a series of Si-derivatized rhodamine (SiR) dyes for their ability to visualize a model drug in live cells. We show that a charge neutral SiR derivative (but not others) can indeed be used to follow the intracellular location of the model therapeutic drug in GFP cells.

Graphical abstract: Red Si–rhodamine drug conjugates enable imaging in GFP cells

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Publication details

The article was received on 07 Jan 2014, accepted on 13 Mar 2014 and first published on 19 Mar 2014


Article type: Communication
DOI: 10.1039/C4CC00144C
Citation: Chem. Commun., 2014,50, 4504-4507
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    Red Si–rhodamine drug conjugates enable imaging in GFP cells

    E. Kim, K. S. Yang, R. J. Giedt and R. Weissleder, Chem. Commun., 2014, 50, 4504
    DOI: 10.1039/C4CC00144C

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