Jump to main content
Jump to site search

Issue 96, 2014
Previous Article Next Article

A quartz crystal microbalance method to study the terminal functionalization of glycosaminoglycans

Author affiliations

Abstract

We demonstrate the quartz crystal microbalance as a novel method to quantify the reaction yields and stability of the terminal conjugation of chemically complex molecules. Oxime ligation is identified as a facile, broadly applicable method for the reducing-end conjugation of glycosaminoglycans that overcomes the limited stability and yield of popular hydrazone ligation.

Graphical abstract: A quartz crystal microbalance method to study the terminal functionalization of glycosaminoglycans

Back to tab navigation

Supplementary files

Publication details

The article was received on 01 Sep 2014, accepted on 16 Oct 2014 and first published on 16 Oct 2014


Article type: Communication
DOI: 10.1039/C4CC06905F
Author version available: Download Author version (PDF)
Citation: Chem. Commun., 2014,50, 15148-15151
  •   Request permissions

    A quartz crystal microbalance method to study the terminal functionalization of glycosaminoglycans

    D. Thakar, E. Migliorini, L. Coche-Guerente, R. Sadir, H. Lortat-Jacob, D. Boturyn, O. Renaudet, P. Labbe and R. P. Richter, Chem. Commun., 2014, 50, 15148
    DOI: 10.1039/C4CC06905F

Search articles by author

Spotlight

Advertisements