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Issue 82, 2014
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Detection of multiple mutations in a single codon of genomic DNA

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Abstract

The controller DNA technology allows the detection of multiple mutations in a single codon of genomic DNA. In this technology, the controller DNA is used to control the hybridization of target DNAs with the immobilized DNAs. The controller DNA technology is rapid, specific, and cost-effective for the following reasons, (i) final results in 40 min after PCR, (ii) detection and discrimination of the six mutations in a single codon, and (iii) high sensitivity.

Graphical abstract: Detection of multiple mutations in a single codon of genomic DNA

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Publication details

The article was received on 08 Aug 2014, accepted on 26 Aug 2014 and first published on 26 Aug 2014


Article type: Communication
DOI: 10.1039/C4CC06220E
Citation: Chem. Commun., 2014,50, 12344-12347
  • Open access: Creative Commons BY license
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    Detection of multiple mutations in a single codon of genomic DNA

    D. R. Sayyed, S. B. Nimse, K. Song and T. Kim, Chem. Commun., 2014, 50, 12344
    DOI: 10.1039/C4CC06220E

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