A highly versatile convergent/divergent “onion peel” synthetic strategy toward potent multivalent glycodendrimers

Rishi Sharma; Naresh Kottari; Yoann M. Chabre; Leïla Abbassi; Tze Chieh Shiao; René Roy

doi:10.1039/C4CC06191H

A highly versatile convergent/divergent “onion peel” synthetic strategy toward potent multivalent glycodendrimers

Rishi Sharma,^a Naresh Kottari,^a Yoann M. Chabre,^a Leïla Abbassi,^a Tze Chieh Shiao^a and René Roy*^a

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* Corresponding authors

^a Pharmaqam, Department of Chemistry, University of Quebec a Montreal, C.P. 8888, Succ. Centre-Ville, Montreal, Canada H3C 3P8
E-mail: roy.rene@uqam.ca

Abstract

Both convergent and divergent strategies for the synthesis of “onion peel” glycodendrimers are reported which resulted in one of the best multivalent ligands known against the virulent factor from a bacterial lectin isolated from Pseudomonas aeruginosa.

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Publication details

The article was received on 07 Aug 2014, accepted on 04 Sep 2014 and first published on 04 Sep 2014

Article type: Communication

DOI: 10.1039/C4CC06191H

Author version available: Download Author version (PDF)

Citation: Chem. Commun., 2014,50, 13300-13303

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A highly versatile convergent/divergent “onion peel” synthetic strategy toward potent multivalent glycodendrimers

R. Sharma, N. Kottari, Y. M. Chabre, L. Abbassi, T. C. Shiao and R. Roy, Chem. Commun., 2014, 50, 13300
DOI: 10.1039/C4CC06191H
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Chemical Communications

A highly versatile convergent/divergent “onion peel” synthetic strategy toward potent multivalent glycodendrimers

Abstract

Supplementary files

Publication details

A highly versatile convergent/divergent “onion peel” synthetic strategy toward potent multivalent glycodendrimers

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