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Issue 86, 2014
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Monovalent maleimide functionalization of gold nanoparticles via copper-free click chemistry

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Abstract

A single maleimide was installed onto the self-assembled monolayer of gold nanoparticles by copper-free click chemistry. Simple covalent biofunctionalisation is demonstrated by coupling fibroblast growth factor 2 and an oligosaccharide in a 1 : 1 stoichiometry by thiol-Michael addition.

Graphical abstract: Monovalent maleimide functionalization of gold nanoparticles via copper-free click chemistry

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Publication details

The article was received on 29 Jul 2014, accepted on 09 Sep 2014 and first published on 09 Sep 2014


Article type: Communication
DOI: 10.1039/C4CC05909C
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Citation: Chem. Commun., 2014,50, 13157-13160
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    Monovalent maleimide functionalization of gold nanoparticles via copper-free click chemistry

    D. J. Nieves, N. S. Azmi, R. Xu, R. Lévy, E. A. Yates and D. G. Fernig, Chem. Commun., 2014, 50, 13157
    DOI: 10.1039/C4CC05909C

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