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Issue 80, 2014
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A highly selective fluorescent probe for hypochlorite and its endogenous imaging in living cells

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Abstract

An oxime based fluorescent probe has been designed and synthesized, which detects free as well as enzymatically generated hypochlorite with a low detection limit and high sensitivity. In addition, the probe was successfully utilized for the monitoring of endogenously produced hypochlorite in LPS stimulated cell lines, C6 glioma and BV2 microglia.

Graphical abstract: A highly selective fluorescent probe for hypochlorite and its endogenous imaging in living cells

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Publication details

The article was received on 11 Jul 2014, accepted on 16 Aug 2014 and first published on 18 Aug 2014


Article type: Communication
DOI: 10.1039/C4CC05356G
Citation: Chem. Commun., 2014,50, 11911-11914
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    A highly selective fluorescent probe for hypochlorite and its endogenous imaging in living cells

    S. I. Reja, V. Bhalla, A. Sharma, G. Kaur and M. Kumar, Chem. Commun., 2014, 50, 11911
    DOI: 10.1039/C4CC05356G

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