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A RCA-based assay for analyzing individual strand break in DNA heteroduplex cleavage by restriction endonucleases

Guojie Zhao,a   Tianyu Hu,a   Jun Li,a   Hua Wei,b   Hong Shangc and   Yifu Guan*a  
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a
Key Laboratory of Medical Cell Biology (Ministry of Education), Department of Biochemistry and Molecular Biology, China Medical University, Shenyang, China
E-mail: yfguan@mail.cmu.edu.cn
b
Animal Science and Veterinary Medicine College, Shenyang Agricultural University, Shenyang, China
c
Department of Clinical Diagnosis, the First Affiliated Hospital, China Medical University, Shenyang, China
Chem. Commun., 2014,50, 11930-11933

DOI: 10.1039/C4CC05314A
Received 12 Jul 2014, Accepted 13 Aug 2014
First published online 13 Aug 2014
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