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Issue 79, 2014
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Rapid engineering of versatile molecular logic gates using heterologous genetic transcriptional modules

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Abstract

We designed and constructed versatile modular genetic logic gates in bacterial cells. These function as digital logic 1-input Buffer gate, 2-input and 3-input AND gates with one inverted input and integrate multiple chemical input signals in customised logic manners. Such rapidly engineered devices serve to achieve increased sensing signal selectivity.

Graphical abstract: Rapid engineering of versatile molecular logic gates using heterologous genetic transcriptional modules

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Publication details

The article was received on 08 Jul 2014, accepted on 21 Jul 2014 and first published on 21 Jul 2014


Article type: Communication
DOI: 10.1039/C4CC05264A
Citation: Chem. Commun., 2014,50, 11642-11644
  • Open access: Creative Commons BY-NC license
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    Rapid engineering of versatile molecular logic gates using heterologous genetic transcriptional modules

    B. Wang and M. Buck, Chem. Commun., 2014, 50, 11642
    DOI: 10.1039/C4CC05264A

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