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Issue 75, 2014
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Cyclometalated Ir(III) complexes as targeted theranostic anticancer therapeutics: combining HDAC inhibition with photodynamic therapy

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Abstract

The successful design and anticancer mechanistic studies of a series of cyclometalated Ir(III) complexes with histone deacetylase inhibitory and photodynamic therapy (PDT) activities are reported.

Graphical abstract: Cyclometalated Ir(iii) complexes as targeted theranostic anticancer therapeutics: combining HDAC inhibition with photodynamic therapy

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Publication details

The article was received on 07 Jul 2014, accepted on 29 Jul 2014 and first published on 30 Jul 2014


Article type: Communication
DOI: 10.1039/C4CC05215C
Citation: Chem. Commun., 2014,50, 10945-10948
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    Cyclometalated Ir(III) complexes as targeted theranostic anticancer therapeutics: combining HDAC inhibition with photodynamic therapy

    R. Ye, C. Tan, L. He, M. Chen, L. Ji and Z. Mao, Chem. Commun., 2014, 50, 10945
    DOI: 10.1039/C4CC05215C

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