Issue 67, 2014

Palladium-catalyzed asymmetric hydrogenation of 3-phthalimido substituted quinolines

Abstract

Homogeneous Pd-catalyzed asymmetric hydrogenation of 3-phthalimido substituted quinolines was successfully developed, providing facile access to chiral substituted tetrahydroquinolines bearing two contiguous stereogenic centers with up to 90% ee.

Graphical abstract: Palladium-catalyzed asymmetric hydrogenation of 3-phthalimido substituted quinolines

Supplementary files

Article information

Article type
Communication
Submitted
09 Jun 2014
Accepted
04 Jul 2014
First published
04 Jul 2014

Chem. Commun., 2014,50, 9588-9590

Author version available

Palladium-catalyzed asymmetric hydrogenation of 3-phthalimido substituted quinolines

X. Cai, W. Huang, Z. Chen and Y. Zhou, Chem. Commun., 2014, 50, 9588 DOI: 10.1039/C4CC04386C

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