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Issue 73, 2014
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Smart dual-functional warhead for folate receptor-specific activatable imaging and photodynamic therapy

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Abstract

A smart dual-targeted theranostic agent becomes highly fluorescent and phototoxic only when its linker is cleaved by tumor-associated lysosomal enzyme cathepsin B after internalization into folate receptor-positive cancer cells.

Graphical abstract: Smart dual-functional warhead for folate receptor-specific activatable imaging and photodynamic therapy

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Publication details

The article was received on 30 May 2014, accepted on 28 Jul 2014 and first published on 28 Jul 2014


Article type: Communication
DOI: 10.1039/C4CC04166F
Citation: Chem. Commun., 2014,50, 10600-10603
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    Smart dual-functional warhead for folate receptor-specific activatable imaging and photodynamic therapy

    J. Kim, C. Tung and Y. Choi, Chem. Commun., 2014, 50, 10600
    DOI: 10.1039/C4CC04166F

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