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Issue 79, 2014
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Promising two-photon probes for in vivo detection of β amyloid deposits

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Abstract

Based on electronic structure calculations we propose that particular small-sized organic molecules – donor–acceptor substituted phenyl polymethines – can be used as two-photon diagnostic probes for non-invasive imaging of amyloid oligomers and fibrils, which are often referred to as the “early signatures” of Alzheimer's disease.

Graphical abstract: Promising two-photon probes for in vivo detection of β amyloid deposits

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Publication details

The article was received on 21 May 2014, accepted on 07 Aug 2014 and first published on 07 Aug 2014


Article type: Communication
DOI: 10.1039/C4CC03897E
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Citation: Chem. Commun., 2014,50, 11694-11697
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    Promising two-photon probes for in vivo detection of β amyloid deposits

    N. A. Murugan, R. Zaleśny, J. Kongsted, A. Nordberg and H. Ågren, Chem. Commun., 2014, 50, 11694
    DOI: 10.1039/C4CC03897E

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