Jump to main content
Jump to site search

Issue 61, 2014
Previous Article Next Article

A copper-mediated oxidative N-cyanation reaction

Author affiliations


Copper-promoted N-cyanation of aliphatic sec-amine by CuCN is achieved via oxidative coupling. This procedure employs O2 as a clean oxidant. Notably, sulfoximines and 1,1,3,3-tetramethylguanidine also worked well in this procedure. Thus, it represents a key progress in the C–N bond formation reaction as well as in the cyanation reaction.

Graphical abstract: A copper-mediated oxidative N-cyanation reaction

Back to tab navigation

Supplementary files

Publication details

The article was received on 07 May 2014, accepted on 04 Jun 2014 and first published on 05 Jun 2014

Article type: Communication
DOI: 10.1039/C4CC03439B
Citation: Chem. Commun., 2014,50, 8412-8415
  •   Request permissions

    A copper-mediated oxidative N-cyanation reaction

    F. Teng, J. Yu, Y. Jiang, H. Yang and J. Cheng, Chem. Commun., 2014, 50, 8412
    DOI: 10.1039/C4CC03439B

Search articles by author