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Benzothiazole derivatives augment glucose uptake in skeletal muscle cells and stimulate insulin secretion from pancreatic β-cells via AMPK activation

L. Pasternak,a   E. Meltzer-Mats,b   G. Babai-Shani,a   G. Cohen,a   O. Viskind,b   J. Eckel,c   E. Cerasi,d   S. Sasson*a and   A. Gruzman*b  
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Corresponding authors
a
Department of Pharmacology, Institute for Drug Research, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel
E-mail: shlomo.sasson@mail.huji.ac.il ;
Tel: +972-2-6758798
b
Department of Chemistry, Faculty of Exact Sciences, Bar-Ilan University, Ramat-Gan, Israel
E-mail: gruzmaa@biu.ac.il ;
Tel: +972-54-7489041
c
German Diabetes Center, Integrative Physiology, Paul-Langerhans-Group, Düsseldorf, Germany
d
The Endocrinology and Metabolism Service, Department of Medicine, Hadassah-Hebrew University Medical Center, Jerusalem, Israel
Chem. Commun., 2014,50, 11222-11225

DOI: 10.1039/C4CC03310H
Received 03 May 2014, Accepted 30 Jul 2014
First published online 30 Jul 2014
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