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Issue 59, 2014
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A new mild synthetic route to N-arylated pyridazinones from aryldiazonium salts

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Abstract

An efficient method for the synthesis of N-arylated pyridazinones from potassium 2-furantrifluoroborate and aryldiazonium salts is described. The reaction was run in water at 0–5 °C in short reaction times and without any catalyst or additive. A mechanistic proposal is made based on the experimental data and DFT calculations.

Graphical abstract: A new mild synthetic route to N-arylated pyridazinones from aryldiazonium salts

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Publication details

The article was received on 29 Apr 2014, accepted on 03 Jun 2014 and first published on 13 Jun 2014


Article type: Communication
DOI: 10.1039/C4CC03190C
Citation: Chem. Commun., 2014,50, 8073-8076
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    A new mild synthetic route to N-arylated pyridazinones from aryldiazonium salts

    O. El Bakouri, D. Cassú, M. Solà, T. Parella, A. Pla-Quintana and A. Roglans, Chem. Commun., 2014, 50, 8073
    DOI: 10.1039/C4CC03190C

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