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Issue 60, 2014
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Tuning the thermosensitive properties of hybrid collagen peptide–polymer hydrogels

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Abstract

A hybrid hydrogel based on collagen-mimetic peptides has been designed with tunable thermosensitive properties. By changing the number of POG repeats within the collagen peptide sequence, the thermal stability of the triple helical physical crosslinks of a peptide–polymer conjugate can be altered, thus tuning the stiffness of the hydrogel as a function of temperature. This report focuses on three different thermally responsive collagen peptide, PEG-based hydrogels and validates their use as stimuli-responsive materials.

Graphical abstract: Tuning the thermosensitive properties of hybrid collagen peptide–polymer hydrogels

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Publication details

The article was received on 29 Apr 2014, accepted on 05 Jun 2014 and first published on 05 Jun 2014


Article type: Communication
DOI: 10.1039/C4CC03171G
Citation: Chem. Commun., 2014,50, 8174-8176
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    Tuning the thermosensitive properties of hybrid collagen peptide–polymer hydrogels

    C. M. Rubert Pérez, L. A. Rank and J. Chmielewski, Chem. Commun., 2014, 50, 8174
    DOI: 10.1039/C4CC03171G

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