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Issue 58, 2014
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Dual pH-triggered multistage drug delivery systems based on host–guest interaction-associated polymeric nanogels

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Abstract

The polymeric nanogels were constructed via host–guest interactions for dual pH-triggered multistage drug delivery, which showed tumor acidity-triggered nanogel reorganization into smaller nanoparticles for deep tissue penetration, high-efficiency cellular uptake, and intracellular endo-lysosomal pH-responsive drug release.

Graphical abstract: Dual pH-triggered multistage drug delivery systems based on host–guest interaction-associated polymeric nanogels

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Publication details

The article was received on 19 Apr 2014, accepted on 27 May 2014 and first published on 02 Jun 2014


Article type: Communication
DOI: 10.1039/C4CC03120B
Citation: Chem. Commun., 2014,50, 7824-7827
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    Dual pH-triggered multistage drug delivery systems based on host–guest interaction-associated polymeric nanogels

    M. Zan, J. Li, S. Luo and Z. Ge, Chem. Commun., 2014, 50, 7824
    DOI: 10.1039/C4CC03120B

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