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Issue 56, 2014
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Microwave-assisted preparation of nucleoside-phosphoramidites

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Abstract

Microwave-assisted phosphitylation of sterically hindered nucleosides is demonstrated to be an efficient method for the preparation of corresponding phosphoramidites (otherwise onerous under standard conditions) and is shown to be general in its applicability.

Graphical abstract: Microwave-assisted preparation of nucleoside-phosphoramidites

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Publication details

The article was received on 25 Apr 2014, accepted on 16 May 2014 and first published on 16 May 2014


Article type: Communication
DOI: 10.1039/C4CC03092C
Author version available: Download Author version (PDF)
Citation: Chem. Commun., 2014,50, 7463-7465
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    Microwave-assisted preparation of nucleoside-phosphoramidites

    G. Meher, T. Efthymiou, M. Stoop and R. Krishnamurthy, Chem. Commun., 2014, 50, 7463
    DOI: 10.1039/C4CC03092C

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