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Issue 61, 2014
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Pd-Catalyzed C–H activation/oxidative cyclization of acetanilide with norbornene: concise access to functionalized indolines

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Abstract

An efficient Pd-catalyzed oxidative cyclization reaction for the synthesis of functionalized indolines by direct C–H activation of acetanilide has been developed. The norbornylpalladium species formed via direct ortho C–H activation of acetanilides is supposed to be a key intermediate in this transformation.

Graphical abstract: Pd-Catalyzed C–H activation/oxidative cyclization of acetanilide with norbornene: concise access to functionalized indolines

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Publication details

The article was received on 24 Apr 2014, accepted on 02 Jun 2014 and first published on 18 Jun 2014


Article type: Communication
DOI: 10.1039/C4CC03062A
Citation: Chem. Commun., 2014,50, 8370-8373
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    Pd-Catalyzed C–H activation/oxidative cyclization of acetanilide with norbornene: concise access to functionalized indolines

    Y. Gao, Y. Huang, W. Wu, K. Huang and H. Jiang, Chem. Commun., 2014, 50, 8370
    DOI: 10.1039/C4CC03062A

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