Issue 61, 2014

High-throughput production of two disulphide-bridge toxins

Abstract

A quick and efficient production method compatible with high-throughput screening was developed using 36 toxins belonging to four different families of two disulphide-bridge toxins. Final toxins were characterized using HPLC co-elution, CD and pharmacological studies.

Graphical abstract: High-throughput production of two disulphide-bridge toxins

Supplementary files

Article information

Article type
Communication
Submitted
11 Apr 2014
Accepted
24 May 2014
First published
12 Jun 2014

Chem. Commun., 2014,50, 8408-8411

Author version available

High-throughput production of two disulphide-bridge toxins

G. Upert, G. Mourier, A. Pastor, M. Verdenaud, D. Alili, D. Servent and N. Gilles, Chem. Commun., 2014, 50, 8408 DOI: 10.1039/C4CC02679A

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