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Issue 78, 2014
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Postsynthetic modification of an amino-tagged MOF using peptide coupling reagents: a comparative study

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Abstract

The suitability of four peptide coupling reagents for postsynthetic modification (PSM) of amino-tagged metal–organic frameworks (MOFs) with carboxylic acids was investigated. Mild reaction conditions at room temperature allow effective covalent attachment of drugs and biomolecules inside the pores of MOFs with moderate chemical stability.

Graphical abstract: Postsynthetic modification of an amino-tagged MOF using peptide coupling reagents: a comparative study

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Publication details

The article was received on 10 Apr 2014, accepted on 12 Jun 2014 and first published on 18 Jun 2014


Article type: Communication
DOI: 10.1039/C4CC02650K
Citation: Chem. Commun., 2014,50, 11472-11475
  • Open access: Creative Commons BY license
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    Postsynthetic modification of an amino-tagged MOF using peptide coupling reagents: a comparative study

    H. Hintz and S. Wuttke, Chem. Commun., 2014, 50, 11472
    DOI: 10.1039/C4CC02650K

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