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Issue 55, 2014
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Monitoring enzymatic ATP hydrolysis by EPR spectroscopy

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Abstract

An adenosine triphosphate (ATP) analogue modified with two nitroxide radicals is developed and employed to study its enzymatic hydrolysis by electron paramagnetic resonance spectroscopy. For this application, we demonstrate that EPR holds the potential to complement fluorogenic substrate analogues in monitoring enzymatic activity.

Graphical abstract: Monitoring enzymatic ATP hydrolysis by EPR spectroscopy

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Publication details

The article was received on 02 Apr 2014, accepted on 07 May 2014 and first published on 15 May 2014


Article type: Communication
DOI: 10.1039/C4CC02422B
Citation: Chem. Commun., 2014,50, 7262-7264
  • Open access: Creative Commons BY license
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    Monitoring enzymatic ATP hydrolysis by EPR spectroscopy

    S. M. Hacker, C. Hintze, A. Marx and M. Drescher, Chem. Commun., 2014, 50, 7262
    DOI: 10.1039/C4CC02422B

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