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Issue 55, 2014
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Intracellular gold nanoparticle aggregation and their potential applications in photodynamic therapy

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Abstract

Gold nanoparticles (Au NPs) with opposite surface charge can form aggregates through electrostatic interaction and exhibit surface plasmon resonance (SPR) induced-localized electromagnetic (EM) field enhancement under light irradiation. Intracellular aggregation of Au NPs can further improve the therapeutic efficiency of Au NP-enhanced photodynamic therapy of cancer by promoting singlet oxygen generation.

Graphical abstract: Intracellular gold nanoparticle aggregation and their potential applications in photodynamic therapy

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Publication details

The article was received on 31 Mar 2014, accepted on 18 May 2014 and first published on 20 May 2014


Article type: Communication
DOI: 10.1039/C4CC02376E
Citation: Chem. Commun., 2014,50, 7287-7290
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    Intracellular gold nanoparticle aggregation and their potential applications in photodynamic therapy

    Y. Yang, Y. Hu, H. Du and H. Wang, Chem. Commun., 2014, 50, 7287
    DOI: 10.1039/C4CC02376E

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