Issue 55, 2014

Intracellular gold nanoparticle aggregation and their potential applications in photodynamic therapy

Abstract

Gold nanoparticles (Au NPs) with opposite surface charge can form aggregates through electrostatic interaction and exhibit surface plasmon resonance (SPR) induced-localized electromagnetic (EM) field enhancement under light irradiation. Intracellular aggregation of Au NPs can further improve the therapeutic efficiency of Au NP-enhanced photodynamic therapy of cancer by promoting singlet oxygen generation.

Graphical abstract: Intracellular gold nanoparticle aggregation and their potential applications in photodynamic therapy

Supplementary files

Article information

Article type
Communication
Submitted
31 Mar 2014
Accepted
18 May 2014
First published
20 May 2014

Chem. Commun., 2014,50, 7287-7290

Intracellular gold nanoparticle aggregation and their potential applications in photodynamic therapy

Y. Yang, Y. Hu, H. Du and H. Wang, Chem. Commun., 2014, 50, 7287 DOI: 10.1039/C4CC02376E

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