Jump to main content
Jump to site search

Issue 61, 2014
Previous Article Next Article

The X-ray structure of the complex formed in the reaction between oxaliplatin and lysozyme

Author affiliations

Abstract

The X-ray structure of the adduct formed between oxaliplatin and the model protein hen egg white lysozyme is reported here. The structure is compared with those of cisplatin and carboplatin derivatives, previously solved. Relevant changes are highlighted among these crystal structures that are suggestive of significant differences in the reactivity of platinum drugs with this protein; possible biological implications are discussed.

Graphical abstract: The X-ray structure of the complex formed in the reaction between oxaliplatin and lysozyme

Back to tab navigation

Supplementary files

Publication details

The article was received on 26 Mar 2014, accepted on 10 Jun 2014 and first published on 10 Jun 2014


Article type: Communication
DOI: 10.1039/C4CC02254H
Citation: Chem. Commun., 2014,50, 8360-8362
  •   Request permissions

    The X-ray structure of the complex formed in the reaction between oxaliplatin and lysozyme

    L. Messori, T. Marzo and A. Merlino, Chem. Commun., 2014, 50, 8360
    DOI: 10.1039/C4CC02254H

Search articles by author

Spotlight

Advertisements