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Issue 61, 2014
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Amphiphilic phthalocyanine–cyclodextrin conjugates for cancer photodynamic therapy

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Abstract

Three phthalocyanines (Pcs) conjugated with α-, β- and γ-cyclodextrins (CDs) were prepared and their application as photosensitizer (PS) agents was assessed by photophysical, photochemical and in vitro photobiological studies. The photoactivity of Pc-α-CD and Pc-γ-CD ensures their potential as PDT drugs against UM-UC-3 human bladder cancer cells.

Graphical abstract: Amphiphilic phthalocyanine–cyclodextrin conjugates for cancer photodynamic therapy

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Publication details

The article was received on 26 Mar 2014, accepted on 10 Jun 2014 and first published on 10 Jun 2014


Article type: Communication
DOI: 10.1039/C4CC02226B
Author version available: Download Author version (PDF)
Citation: Chem. Commun., 2014,50, 8363-8366
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    Amphiphilic phthalocyanine–cyclodextrin conjugates for cancer photodynamic therapy

    L. M. O. Lourenço, P. M. R. Pereira, E. Maciel, M. Válega, F. M. J. Domingues, M. R. M. Domingues, M. G. P. M. S. Neves, J. A. S. Cavaleiro, R. Fernandes and J. P. C. Tomé, Chem. Commun., 2014, 50, 8363
    DOI: 10.1039/C4CC02226B

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