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Issue 46, 2014
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A novel family of structurally stable double stranded DNA catenanes

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Abstract

Here we describe the design, assembly and characterisation of different structurally stable and highly polyvalent DNA catenanes. We synthesized a series of different catenated DNA nanostructures, among them symmetric ones containing two 126 or 168 base-pair rings, non-symmetric ones with a 126 and a 168 base-pair ring, and a [3]catenane containing three 126 base-pair rings. Reversible and quantitative on/off switching of the mobility of the rings was demonstrated as a proof-of-concept for the employment of these catenanes as dynamic DNA-nanostructures.

Graphical abstract: A novel family of structurally stable double stranded DNA catenanes

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Publication details

The article was received on 18 Mar 2014, accepted on 14 Apr 2014 and first published on 15 Apr 2014


Article type: Communication
DOI: 10.1039/C4CC02030H
Citation: Chem. Commun., 2014,50, 6091-6093
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    A novel family of structurally stable double stranded DNA catenanes

    F. Lohmann, J. Valero and M. Famulok, Chem. Commun., 2014, 50, 6091
    DOI: 10.1039/C4CC02030H

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