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One-pot enantioselective construction of indoloquinolizidine derivatives bearing five contiguous stereocenters using aliphatic aldehydes, nitroethylenes, and tryptamine

Yu Tan,a   Han-Lin Luan,a   Hua Lin,a   Xing-Wen Sun,*a   Xiao-Di Yang,a   Han-Qing Dongbc and   Guo-Qiang Lin*ab  
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Department of Chemistry, Fudan University, 220 Handan Road, Shanghai 200433, China
E-mail: sunxingwen@fudan.edu.cn, lingq@sioc.ac.cn;
Fax: +86 21 5566 4460 ;
Tel: +86 21 5566 4460
Shanghai Institute of Organic Chemistry, 354 Lingling Road, Shanghai 200032, China
Arvinas Inc., 5 Science Park, New Haven, USA
Chem. Commun., 2014, Advance Article

DOI: 10.1039/C4CC01929F
Received 15 Mar 2014, Accepted 01 May 2014
First published online 02 May 2014
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