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Issue 43, 2014
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Novel syntheses of aryl quinoxaline C-nucleoside analogs by mild and efficient three-component sequential reactions

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Abstract

Novel syntheses of C-nucleoside analogs with aryl quinoxalines as nucleobase surrogates have been accomplished by mild and efficient three-component sequential reactions in high yields with a wide scope of substrates. The mechanism was clarified by isolation of novel sugar 1,2-diketone derived from oxidation of the corresponding alkyne.

Graphical abstract: Novel syntheses of aryl quinoxaline C-nucleoside analogs by mild and efficient three-component sequential reactions

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Publication details

The article was received on 25 Feb 2014, accepted on 11 Apr 2014 and first published on 11 Apr 2014


Article type: Communication
DOI: 10.1039/C4CC01448K
Citation: Chem. Commun., 2014,50, 5771-5773
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    Novel syntheses of aryl quinoxaline C-nucleoside analogs by mild and efficient three-component sequential reactions

    F. Zhang, Y. Xi, Y. Lu, L. Wang, L. Liu, J. Li and Y. Zhao, Chem. Commun., 2014, 50, 5771
    DOI: 10.1039/C4CC01448K

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