Jump to main content
Jump to site search
PLANNED MAINTENANCE Close the message box

Scheduled maintenance upgrade on Thursday 4th of May 2017 from 8.00am to 9.00am (BST).

During this time our websites will be offline temporarily. If you have any questions please use the feedback button on this page. We apologise for any inconvenience this might cause and thank you for your patience.


Issue 41, 2014
Previous Article Next Article

Biocatalytic amide condensation and gelation controlled by light

Author affiliations

Abstract

We report on a supramolecular self-assembly system that displays coupled light switching, biocatalytic condensation/hydrolysis and gelation. The equilibrium state of this system can be regulated by light, favouring in situ formation, by protease catalysed peptide synthesis, of self-assembling trans-Azo-YF-NH2 in ambient light; however, irradiation with UV light gives rise to the cis-isomer, which readily hydrolyzes to its amino acid derivatives (cis-Azo-Y + F-NH2) with consequent gel dissolution.

Graphical abstract: Biocatalytic amide condensation and gelation controlled by light

Back to tab navigation
Please wait while Download options loads

Supplementary files

Publication details

The article was received on 24 Feb 2014, accepted on 25 Mar 2014 and first published on 25 Mar 2014


Article type: Communication
DOI: 10.1039/C4CC01431F
Citation: Chem. Commun., 2014,50, 5462-5464
  •   Request permissions

    Biocatalytic amide condensation and gelation controlled by light

    J. K. Sahoo, S. K. M. Nalluri, N. Javid, H. Webb and R. V. Ulijn, Chem. Commun., 2014, 50, 5462
    DOI: 10.1039/C4CC01431F

Search articles by author