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Asymmetric synthesis of heteroaryl atropisomers via a gold-catalyzed cycloisomerization–amination cascade reaction

Rui Guo,a   Kang-Nan Li,a   Bin Liu,a   Hua-Jie Zhu,*b   Yu-Meng Fana and   Liu-Zhu Gong*a  
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Hefei National Laboratory for Physical Sciences at the Microscale and Department of Chemistry, University of Science and Technology of China, Hefei, China
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Chinese Centre for Chirality, Key Laboratory of Medicinal Chemistry and Molecular Diagnostics of Education Administration of China, College of Pharmacy Sciences, Hebei University, Baoding, China
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Chem. Commun., 2014,50, 5451-5454

DOI: 10.1039/C4CC01397B
Received 23 Feb 2014, Accepted 19 Mar 2014
First published online 20 Mar 2014
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