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Biotin-conjugated N-methylisatoic anhydride: a chemical tool for nucleic acid separation by selective 2′-hydroxyl acylation of RNA

S. Ursuegui,ab   N. Chivot,c   S. Moutin,c   A. Burr,c   C. Fossey,ab   T. Cailly,ab   A. Laayoun,c   F. Fabis*ab and   A. Laurent*c  
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a
Normandie Univ, France
b
Université de Caen Basse-Normandie, Centre d'Etudes et de Recherche sur le Médicament de Normandie (EA 4258 - FR CNRS 3038 INC3M - SF 4206 ICORE) UFR des Sciences Pharmaceutiques, Bd Becquerel, F-14032 Caen, France
E-mail: frederic.fabis@unicaen.fr
c
BioMérieux SA, Centre Christophe Mérieux, Parc Polytech, 5 rue des berges, 38024 Grenoble, France
E-mail: alain.laurent@biomerieux.com
Chem. Commun., 2014,50, 5748-5751

DOI: 10.1039/C4CC01134A
Received 12 Feb 2014, Accepted 07 Apr 2014
First published online 07 Apr 2014
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