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Issue 61, 2014
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A fluorescent light-up probe with AIE characteristics for specific mitochondrial imaging to identify differentiating brown adipose cells

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Abstract

We report the design and synthesis of a specific mitochondrial fluorescent probe AIE-MitoGreen-1 with AIE characteristics to monitor the mitochondrial morphology changes and identify the differentiation process of living brown adipose cells. The probe AIE-MitoGreen-1 has significant advantages such as high cell-permeability, good mitochondrial retention, low background fluorescence, large Stokes shift, and low toxicity.

Graphical abstract: A fluorescent light-up probe with AIE characteristics for specific mitochondrial imaging to identify differentiating brown adipose cells

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Publication details

The article was received on 19 Jan 2014, accepted on 09 Jun 2014 and first published on 09 Jun 2014


Article type: Communication
DOI: 10.1039/C4CC00452C
Citation: Chem. Commun., 2014,50, 8312-8315
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    A fluorescent light-up probe with AIE characteristics for specific mitochondrial imaging to identify differentiating brown adipose cells

    M. Gao, C. K. Sim, C. W. T. Leung, Q. Hu, G. Feng, F. Xu, B. Z. Tang and B. Liu, Chem. Commun., 2014, 50, 8312
    DOI: 10.1039/C4CC00452C

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