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Issue 31, 2014
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Iron-catalyzed aerobic difunctionalization of alkenes: a highly efficient approach to construct oxindoles by C–S and C–C bond formation

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Abstract

A novel iron-catalyzed efficient approach to construct sulfone-containing oxindoles, which play important roles in the structural library design and drug discovery, has been developed. The use of readily available benzenesulfinic acids, an inexpensive iron salt as the catalyst, and air as the oxidant makes this sulfur incorporation protocol very efficient and practical.

Graphical abstract: Iron-catalyzed aerobic difunctionalization of alkenes: a highly efficient approach to construct oxindoles by C–S and C–C bond formation

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Publication details

The article was received on 17 Jan 2014, accepted on 26 Feb 2014 and first published on 26 Feb 2014


Article type: Communication
DOI: 10.1039/C4CC00401A
Citation: Chem. Commun., 2014,50, 4115-4118
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    Iron-catalyzed aerobic difunctionalization of alkenes: a highly efficient approach to construct oxindoles by C–S and C–C bond formation

    T. Shen, Y. Yuan, S. Song and N. Jiao, Chem. Commun., 2014, 50, 4115
    DOI: 10.1039/C4CC00401A

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