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Issue 33, 2014
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Proteome reactivity profiling for the discrimination of pathogenic bacteria

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Abstract

Diverse proteome reactivity profiles were obtained using small-molecule electrophiles. Based on the cross-reactivity profile, each protein generated a unique reactivity fingerprint. Here, we report the first proteome reactivity signature-based discrimination of 11 bacteria. Perfect differentiation of 11 bacteria can be achieved using 2 benzyl-halide probes.

Graphical abstract: Proteome reactivity profiling for the discrimination of pathogenic bacteria

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Publication details

The article was received on 15 Jan 2014, accepted on 06 Mar 2014 and first published on 07 Mar 2014


Article type: Communication
DOI: 10.1039/C4CC00320A
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Citation: Chem. Commun., 2014,50, 4347-4350
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    Proteome reactivity profiling for the discrimination of pathogenic bacteria

    J. Lee, Y. Yoo, J. Kang, W. S. Han, J. K. Lee and C. N. Yoon, Chem. Commun., 2014, 50, 4347
    DOI: 10.1039/C4CC00320A

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