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Issue 22, 2014
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Electrochemiluminescence signal amplification combined with a conformation-switched hairpin DNA probe for determining the methylation level and position in the Hsp53 tumor suppressor gene

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Abstract

We report a new strategy for detection of the methylation level and position in the Hsp53 tumor suppressor gene based on the electrochemiluminescence signal amplification combined with a conformation-switched hairpin DNA probe for improving selectivity.

Graphical abstract: Electrochemiluminescence signal amplification combined with a conformation-switched hairpin DNA probe for determining the methylation level and position in the Hsp53 tumor suppressor gene

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Publication details

The article was received on 23 Dec 2013, accepted on 23 Jan 2014 and first published on 24 Jan 2014


Article type: Communication
DOI: 10.1039/C3CC49719D
Author version available: Download Author version (PDF)
Citation: Chem. Commun., 2014,50, 2932-2934
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    Electrochemiluminescence signal amplification combined with a conformation-switched hairpin DNA probe for determining the methylation level and position in the Hsp53 tumor suppressor gene

    H. Zhang, M. Li, M. Fan, J. Gu, P. Wu and C. Cai, Chem. Commun., 2014, 50, 2932
    DOI: 10.1039/C3CC49719D

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