Issue 25, 2014

Enantioselective, intermolecular [2+2] photocycloaddition reactions of 3-acetoxyquinolone: total synthesis of (−)-pinolinone

Abstract

The natural product (−)-pinolinone was synthesised via a concise route (six steps, 17% overall yield) from 3-acetoxyquinolone, employing an enantioselective intermolecular [2+2] photocycloaddition as the key step.

Graphical abstract: Enantioselective, intermolecular [2+2] photocycloaddition reactions of 3-acetoxyquinolone: total synthesis of (−)-pinolinone

Supplementary files

Article information

Article type
Communication
Submitted
13 Dec 2013
Accepted
07 Feb 2014
First published
18 Feb 2014
This article is Open Access
Creative Commons BY-NC license

Chem. Commun., 2014,50, 3353-3355

Author version available

Enantioselective, intermolecular [2+2] photocycloaddition reactions of 3-acetoxyquinolone: total synthesis of (−)-pinolinone

F. Mayr, C. Wiegand and T. Bach, Chem. Commun., 2014, 50, 3353 DOI: 10.1039/C3CC49469A

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