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Issue 23, 2014
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Supramolecular polymeric peptide amphiphile vesicles for the encapsulation of basic fibroblast growth factor

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Abstract

The synthesis of a supramolecular double hydrophilic peptide-conjugated polymer held together by cucurbit[8]uril (CB[8]) ternary complexation and its subsequent temperature triggered self-assembly into vesicles are described. Basic fibroblast growth factor can be easily loaded into the vesicles under benign conditions and their bioactivities can be preserved without the need for excipients such as heparin.

Graphical abstract: Supramolecular polymeric peptide amphiphile vesicles for the encapsulation of basic fibroblast growth factor

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Publication details

The article was received on 28 Nov 2013, accepted on 06 Jan 2014 and first published on 07 Jan 2014


Article type: Communication
DOI: 10.1039/C3CC49074B
Citation: Chem. Commun., 2014,50, 3033-3035
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    Supramolecular polymeric peptide amphiphile vesicles for the encapsulation of basic fibroblast growth factor

    X. J. Loh, J. del Barrio, T. Lee and O. A. Scherman, Chem. Commun., 2014, 50, 3033
    DOI: 10.1039/C3CC49074B

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