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Issue 32, 2014
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A lysosome-specific two-photon phosphorescent binuclear cyclometalated platinum(II) probe for in vivo imaging of live neurons

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Abstract

Real-time tracking of fast axonal transport of acidic vesicles in live adult mouse dorsal root ganglion (DRG) and cortical neurons in brain slices was visualized by the use of binuclear cycloplatinated complexes, {[Pt(L1)]2(μ-dppm)}2+ (1) and {[Pt(L2)]2(μ-dppm)}2+ (2), as lysosome-specific two-photon imaging probes.

Graphical abstract: A lysosome-specific two-photon phosphorescent binuclear cyclometalated platinum(ii) probe for in vivo imaging of live neurons

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The article was received on 22 Nov 2013, accepted on 24 Dec 2013 and first published on 03 Jan 2014


Article type: Communication
DOI: 10.1039/C3CC48934E
Citation: Chem. Commun., 2014,50, 4161-4163
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    A lysosome-specific two-photon phosphorescent binuclear cyclometalated platinum(II) probe for in vivo imaging of live neurons

    Y. Ho, N. B. Au, K. Wong, C. T. Chan, W. Kwok, G. Law, K. Tang, W. Wong, C. E. Ma and M. H. Lam, Chem. Commun., 2014, 50, 4161
    DOI: 10.1039/C3CC48934E

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