Jump to main content
Jump to site search

Issue 39, 2014
Previous Article Next Article

Direct N9-arylation of purines with aryl halides

Author affiliations

Abstract

An efficient method for N-arylation of purines is reported. The N-arylation is catalysed by Cu(I) and 4,7-bis(2-hydroxyethylamino)-1,10-phenanthroline (BHPhen) in aqueous DMF or ethanol. The reaction generally proceeds with high selectivity for the N9-position.

Graphical abstract: Direct N9-arylation of purines with aryl halides

Back to tab navigation

Supplementary files

Publication details

The article was received on 12 Nov 2013, accepted on 10 Feb 2014 and first published on 12 Feb 2014


Article type: Communication
DOI: 10.1039/C3CC48642G
Citation: Chem. Commun., 2014,50, 4997-4999
  • Open access: Creative Commons BY-NC license
  •   Request permissions

    Direct N9-arylation of purines with aryl halides

    A. F. Larsen and T. Ulven, Chem. Commun., 2014, 50, 4997
    DOI: 10.1039/C3CC48642G

    This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence. Material from this article can be used in other publications provided that the correct acknowledgement is given with the reproduced material and it is not used for commercial purposes.

    Reproduced material should be attributed as follows:

    • For reproduction of material from NJC:
      [Original citation] - Published by The Royal Society of Chemistry (RSC) on behalf of the Centre National de la Recherche Scientifique (CNRS) and the RSC.
    • For reproduction of material from PCCP:
      [Original citation] - Published by the PCCP Owner Societies.
    • For reproduction of material from PPS:
      [Original citation] - Published by The Royal Society of Chemistry (RSC) on behalf of the European Society for Photobiology, the European Photochemistry Association, and RSC.
    • For reproduction of material from all other RSC journals:
      [Original citation] - Published by The Royal Society of Chemistry.

    Information about reproducing material from RSC articles with different licences is available on our Permission Requests page.

Search articles by author

Spotlight

Advertisements