Jump to main content
Jump to site search

Issue 19, 2014
Previous Article Next Article

Ni(II)–salt catalyzed activation of primary amine-sp3Cα–H and cyclization with 1,2-diketone to tetrasubstituted imidazoles

Author affiliations

Abstract

NiCl2·6H2O and Ni(OAc)2·4H2O were found as efficient catalysts for C–H activation of benzyl and aliphatic amines for an unprecedented multi C–N bond forming cyclization with 1,2-diketones under refluxing toluene to furnish highly substituted and polycyclic imidazoles.

Graphical abstract: Ni(ii)–salt catalyzed activation of primary amine-sp3Cα–H and cyclization with 1,2-diketone to tetrasubstituted imidazoles

Back to tab navigation

Supplementary files

Publication details

The article was received on 04 Nov 2013, accepted on 03 Dec 2013 and first published on 03 Dec 2013


Article type: Communication
DOI: 10.1039/C3CC48437H
Citation: Chem. Commun., 2014,50, 2477-2480
  •   Request permissions

    Ni(II)–salt catalyzed activation of primary amine-sp3Cα–H and cyclization with 1,2-diketone to tetrasubstituted imidazoles

    S. Samanta, D. Roy, S. Khamarui and D. K. Maiti, Chem. Commun., 2014, 50, 2477
    DOI: 10.1039/C3CC48437H

Search articles by author

Spotlight

Advertisements