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Issue 11, 2014
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Co-delivery of small interfering RNA using a camptothecin prodrug as the carrier

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Abstract

We have reported the first effort towards directly using an anticancer prodrug (CPTssR5H5) as a carrier to co-deliver camptothecin (CPT) and small interfering RNA for multidrug resistant cancer chemotherapy. The results indicated that CPTssR5H5 is a promising co-delivery system for MDR cancer therapy.

Graphical abstract: Co-delivery of small interfering RNA using a camptothecin prodrug as the carrier

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Publication details

The article was received on 16 Oct 2013, accepted on 21 Nov 2013 and first published on 17 Dec 2013


Article type: Communication
DOI: 10.1039/C3CC47970F
Citation: Chem. Commun., 2014,50, 1323-1325
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    Co-delivery of small interfering RNA using a camptothecin prodrug as the carrier

    Q. Tang, B. Cao and G. Cheng, Chem. Commun., 2014, 50, 1323
    DOI: 10.1039/C3CC47970F

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