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Issue 8, 2014
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Polyacrylic acid@zeolitic imidazolate framework-8 nanoparticles with ultrahigh drug loading capability for pH-sensitive drug release

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Abstract

The polyacrylic acid@zeolitic imidazolate framework-8 (PAA@ZIF-8) nanoparticles (NPs) were first fabricated using a facile and simple route. It is worthwhile noting that the as-fabricated PAA@ZIF-8 NPs possessed ultrahigh doxorubicin (DOX) loading capability (1.9 g DOX gāˆ’1 NPs), which were employed as pH-dependent drug delivery vehicles.

Graphical abstract: Polyacrylic acid@zeolitic imidazolate framework-8 nanoparticles with ultrahigh drug loading capability for pH-sensitive drug release

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Publication details

The article was received on 06 Oct 2013, accepted on 11 Nov 2013 and first published on 11 Nov 2013


Article type: Communication
DOI: 10.1039/C3CC47666A
Citation: Chem. Commun., 2014,50, 1000-1002
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    Polyacrylic acid@zeolitic imidazolate framework-8 nanoparticles with ultrahigh drug loading capability for pH-sensitive drug release

    H. Ren, L. Zhang, J. An, T. Wang, L. Li, X. Si, L. He, X. Wu, C. Wang and Z. Su, Chem. Commun., 2014, 50, 1000
    DOI: 10.1039/C3CC47666A

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