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Issue 40, 2014
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Multifunctional squalene-based prodrug nanoparticles for targeted cancer therapy

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Abstract

Fluorescent and biotinylated squalene–gemcitabine prodrug nanoparticles exhibiting high drug payloads have been prepared and successfully used to target different cancer cell lines, resulting in increased cell uptake and improved anticancer efficiency, which represents the first targeted system derived from the squalenoylation approach.

Graphical abstract: Multifunctional squalene-based prodrug nanoparticles for targeted cancer therapy

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Publication details

The article was received on 28 Sep 2013, accepted on 17 Oct 2013 and first published on 18 Oct 2013


Article type: Communication
DOI: 10.1039/C3CC47427E
Citation: Chem. Commun., 2014,50, 5336-5338
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    Multifunctional squalene-based prodrug nanoparticles for targeted cancer therapy

    D. T. Bui, J. Nicolas, A. Maksimenko, D. Desmaële and P. Couvreur, Chem. Commun., 2014, 50, 5336
    DOI: 10.1039/C3CC47427E

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