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Issue 6, 2014
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A coumarin derivative as a fluorogenic glycoproteomic probe for biological imaging

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Abstract

Fluorescence imaging in living cells is typically carried out using a functionalized fluorescent dye. But it often causes strong background noise under many conditions where washing is not applicable. Here, we report on a coumarin based fluorogenic probe, which can be used as a bioorthogonal-labeling tool for glycoproteins. The results indicated that the probe was able to image glycoproteins in living cells and it may also be suitable for intracellular imaging.

Graphical abstract: A coumarin derivative as a fluorogenic glycoproteomic probe for biological imaging

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Publication details

The article was received on 25 Sep 2013, accepted on 07 Nov 2013 and first published on 07 Nov 2013


Article type: Communication
DOI: 10.1039/C3CC47323F
Citation: Chem. Commun., 2014,50, 667-669
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    A coumarin derivative as a fluorogenic glycoproteomic probe for biological imaging

    L. Rong, L. Liu, S. Chen, H. Cheng, C. Chen, Z. Li, S. Qin and X. Zhang, Chem. Commun., 2014, 50, 667
    DOI: 10.1039/C3CC47323F

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