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Issue 8, 2014
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Programmed hydrolysis of nanoassemblies by electrostatic interaction-mediated enzymatic-degradation

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Abstract

Electrostatic interaction-mediated enzymatic-hydrolysis of poly(lactide)-containing nanoscale assemblies is described. At physiological pH, degradable core–shell morphologies with charged shells can readily attract or repel enzymes carrying opposite or similar charges, respectively.

Graphical abstract: Programmed hydrolysis of nanoassemblies by electrostatic interaction-mediated enzymatic-degradation

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Publication details

The article was received on 06 Aug 2013, accepted on 25 Nov 2013 and first published on 04 Dec 2013


Article type: Communication
DOI: 10.1039/C3CC46013D
Citation: Chem. Commun., 2014,50, 968-970
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    Programmed hydrolysis of nanoassemblies by electrostatic interaction-mediated enzymatic-degradation

    S. Samarajeewa, R. P. Zentay, N. D. Jhurry, A. Li, K. Seetho, J. Zou and K. L. Wooley, Chem. Commun., 2014, 50, 968
    DOI: 10.1039/C3CC46013D

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