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Issue 24, 2014
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Chemiluminescence diminishment on a paper-based analytical device: high throughput determination of β-agonists in swine hair

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Abstract

β-Agonists are a group of illegal but widely used feed additives in the stockbreeding industry. In order to achieve simple-to-use, fast and high-throughput testing of this banned chemical, herein we suggest a paper-based analytical device on which a chemiluminescence diminishment method was performed. In this approach, extracts from swine hair samples as well as luminescent reagents, such as luminol and potassium periodate solution, in a low volume were applied to our device. It was found that the light emission was diminished by the β-agonists extracted from the swine hair samples. The degree of diminishment is proportional to the concentration of the β-agonists from 1.0 × 10−5 to 1.0 × 10−8 mol L−1. Also, the concentrations of solutions for chemiluminescence were optimized. The mechanism and reaction kinetics of chemiluminescence were discussed as well. The detection limit was obtained as 1.0 × 10−9 mol L−1, and recoveries from 96% to 110% were achieved, both of which suggested that our method will be favourable in field applications for swine hair samples.

Graphical abstract: Chemiluminescence diminishment on a paper-based analytical device: high throughput determination of β-agonists in swine hair

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Publication details

The article was received on 10 Sep 2014, accepted on 18 Oct 2014 and first published on 20 Oct 2014


Article type: Paper
DOI: 10.1039/C4AY02116A
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Citation: Anal. Methods, 2014,6, 9684-9690
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    Chemiluminescence diminishment on a paper-based analytical device: high throughput determination of β-agonists in swine hair

    X. Chen, Y. Luo, B. Shi, X. Liu, Z. Gao, Y. Du, W. Zhao and B. Lin, Anal. Methods, 2014, 6, 9684
    DOI: 10.1039/C4AY02116A

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