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Issue 21, 2014
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Chemical sensing with nanoparticles as optical reporters: from noble metal nanoparticles to quantum dots and upconverting nanoparticles

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Abstract

A wide variety of biological and medical analyses are based on the use of optical signals to report specific molecular events. Thanks to advances in nanotechnology, various nanostructures have been extensively used as optical reporters in bio- and chemical assays. This review describes recent progress in chemical sensing using noble metal nanoparticles (gold and silver), quantum dots and upconverting nanoparticles. It provides insights into various nanoparticle-based sensing strategies including fluorescence/luminescence resonance energy transfer nanoprobes as well as activatable probes sensitive to specific changes in the biological environment. Finally we list some research challenges to be overcome in order to accelerate the development of applications of nanoparticle bio- and chemical sensors.

Graphical abstract: Chemical sensing with nanoparticles as optical reporters: from noble metal nanoparticles to quantum dots and upconverting nanoparticles

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Publication details

The article was received on 15 Jul 2014, accepted on 07 Aug 2014 and first published on 08 Aug 2014


Article type: Minireview
DOI: 10.1039/C4AN01272K
Citation: Analyst, 2014,139, 5321-5334
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    Chemical sensing with nanoparticles as optical reporters: from noble metal nanoparticles to quantum dots and upconverting nanoparticles

    W. Deng and E. M. Goldys, Analyst, 2014, 139, 5321
    DOI: 10.1039/C4AN01272K

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