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Issue 21, 2014
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Green electrochemical sensing platforms: utilizing hydroxyapatite derived from natural fish scales as a novel electrochemical material for the sensitive detection of kidney injury molecule 1 (KIM-1)

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Abstract

Urinary KIM-1 is an ideal biomarker for acute kidney injury diagnosis. The proof-of-concept is demonstrated by utilizing the hydroxyapatite derived from natural fish scales as an electrode material, where the sensing of KIM-1 is shown to be possible for the first time with a linear range from 0.01 to 0.20 μg mL−1 and a detection limit of 0.017 μg mL−1 under model conditions; proof-of-concept is demonstrated in spiked urine.

Graphical abstract: Green electrochemical sensing platforms: utilizing hydroxyapatite derived from natural fish scales as a novel electrochemical material for the sensitive detection of kidney injury molecule 1 (KIM-1)

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Publication details

The article was received on 27 May 2014, accepted on 14 Aug 2014 and first published on 05 Sep 2014


Article type: Communication
DOI: 10.1039/C4AN00957F
Citation: Analyst, 2014,139, 5362-5366
  • Open access: Creative Commons BY-NC license
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    Green electrochemical sensing platforms: utilizing hydroxyapatite derived from natural fish scales as a novel electrochemical material for the sensitive detection of kidney injury molecule 1 (KIM-1)

    Y. Zhang, W. Zhang, Q. Zhang, K. Li, W. Liu, Y. Liu and C. E. Banks, Analyst, 2014, 139, 5362
    DOI: 10.1039/C4AN00957F

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