Jump to main content
Jump to site search

Issue 38, 2013
Previous Article Next Article

Monodisperse collagen–gelatin beads as potential platforms for 3D cell culturing

Author affiliations

Abstract

A droplet-based microfluidics technique is used to produce monodisperse, 80 μm collagen–gelatin beads with tunable mechanical properties in the range of 1–10 kPa after photo-crosslinking. The gel beads are porous, mechanically robust and stable in buffer, but can be degraded enzymatically. Encapsulated fibroblast cells maintain 70% viability after one-week encapsulation and preliminary results show that the degree of spreading of cells in gels is correlated with the stiffness of the material.

Graphical abstract: Monodisperse collagen–gelatin beads as potential platforms for 3D cell culturing

Back to tab navigation

Supplementary files

Publication details

The article was received on 14 Jun 2013, accepted on 04 Aug 2013 and first published on 06 Aug 2013


Article type: Paper
DOI: 10.1039/C3TB20851F
Citation: J. Mater. Chem. B, 2013,1, 5128-5136
  •   Request permissions

    Monodisperse collagen–gelatin beads as potential platforms for 3D cell culturing

    S. Ma, M. Natoli, X. Liu, M. P. Neubauer, F. M. Watt, A. Fery and W. T. S. Huck, J. Mater. Chem. B, 2013, 1, 5128
    DOI: 10.1039/C3TB20851F

Search articles by author

Spotlight

Advertisements